Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
UniProtKB P14003 (HAIR_DROME): Protein hairy
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Hairy represses transcription by forming a complex with the Groucho corepressor, recruited through its C-terminal WRPW motif.
"Interacts with gro (via WPRW motif)"
Huckebein repressor activity in Drosophila terminal patterning is mediated by Groucho.
The origin and evolution of segmentation.
Epithelial tube morphology is determined by the polarized growth and delivery of apical membrane.
Tube morphogenesis: no pipe dream in Drosophila.
The role of class I HLH genes in neural development--have they been overlooked?
Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.
The evolution of arthropod segmentation mechanisms.
A molecular link between FGF and Dpp signaling in branch-specific migration of the Drosophila trachea.
Physical and genetic interactions link hox function with diverse transcription factors and cell signaling proteins.
A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.
Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch.
Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor.
Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression.
Origins of context-dependent gene repression by capicua.
Pair-rule expression of the Drosophila fushi tarazu gene: a nuclear receptor response element mediates the opposing regulatory effects of runt and hairy.
Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete.
The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain.
A network of interacting transcriptional regulators involved in Drosophila neural fate specification revealed by the yeast two-hybrid system.
Drosophila CtBP: a Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repression.
Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo.