Gene Ontology annotation through association of InterPro records with GO terms
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Electronic Gene Ontology annotations created by ARBA machine learning models
TreeGrafter-generated GO annotations
Combined Automated Annotation using Multiple IEA Methods
UniProtKB record A0A0H2M7Y1 (A0A0H2M7Y1_VARPD) - Taurine transport system permease protein TauC from Variovorax paradoxus TBEA6
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VPARA_03670 (tauC, A0A0H2M7Y1) is a 294-aa integral inner-membrane ABC permease protein (InterPro IPR000515, PANTHER PTHR30151:SF25) containing six predicted transmembrane helices and an ABC transmembrane type-1 domain (PROSITE PS50928, residues 100-280).
"FT DOMAIN 100..280
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928""
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VPARA_03670 (tauC) corresponds to EMBL CDS accession KLN58256.1 on genomic contig JZWI01000003, where consecutive CDS accessions (KLN58254.1-KLN58256.1) and locus tags stepping by 10 place tauC immediately downstream of tauA (VPARA_03650, KLN58254.1) and tauB1 (VPARA_03660, KLN58255.1).
"DR EMBL; JZWI01000003; KLN58256.1; -; Genomic_DNA."
Identification of sulfate starvation-regulated genes in Escherichia coli: a gene cluster involved in the utilization of taurine as a sulfur source.
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Characterization of the E. coli tauABCD operon identified TauC as the integral membrane permease subunit of the taurine ABC uptake system.
"The TauA protein contained a putative signal peptide for transport into the periplasm; the TauB and TauC proteins showed sequence similarity to ATP-binding proteins and membrane proteins, respectively, of ABC-type transport systems"
Deletion analysis of the Escherichia coli taurine and alkanesulfonate transport systems.
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Deletion and complementation analysis in E. coli established that TauABC mediates taurine import and its subunits cannot form functional hybrid transporters with SsuABC.
"Mutants in which only formation of hybrid transporters was possible were unable to grow with sulfonates, indicating that the individual components of the two transport systems were not functionally exchangeable."