GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11487543
Intestinal epithelial cells secrete exosome-like vesicles.
PMID:15576373
Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression.
PMID:16339081
Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity.
PMID:17693260
SARA-regulated vesicular targeting underlies formation of the light-sensing organelle in mammalian rods.
PMID:18588921
Involvement of Munc18 isoforms in the regulation of granule exocytosis in neutrophils.
PMID:19056867
Large-scale proteomics and phosphoproteomics of urinary exosomes.
PMID:21720706
Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration.
PMID:24726755
Loss of syntaxin 3 causes variant microvillus inclusion disease.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:26359495
The Q-soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor (Q-SNARE) SNAP-47 Regulates Trafficking of Selected Vesicle-associated Membrane Proteins (VAMPs).
PMID:27662481
The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons.
PMID:29475951
Soluble syntaxin 3 functions as a transcriptional regulator.
PMID:29892012
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.
PMID:31515488
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:40205054
Multimodal cell maps as a foundation for structural and functional genomics.
Reactome:R-HSA-9014052
TXLNA (IL14) binds syntaxin3
PMID:11003604
Transport and function of syntaxin 3 in human epithelial intestinal cells.
PMID:9701566
Interaction of Munc-18-2 with syntaxin 3 controls the association of apical SNAREs in epithelial cells.
PMID:10788461
Munc18-2, a functional partner of syntaxin 3, controls apical membrane trafficking in epithelial cells.
PMID:16785322
Apical targeting of syntaxin 3 is essential for epithelial cell polarity.
PMID:18683220
Syntaxin 3b is a t-SNARE specific for ribbon synapses of the retina.
PMID:20844248
Syntaxin 3 is necessary for cAMP- and cGMP-regulated exocytosis of CFTR: implications for enterotoxigenic diarrhea.
PMID:24323579
Munc18-2 and syntaxin 3 control distinct essential steps in mast cell degranulation.
PMID:30563839
Syntaxin 3, but not syntaxin 4, is required for mast cell-regulated exocytosis, where it plays a primary role mediating compound exocytosis.
PMID:32778589
Syntaxin 3 is essential for photoreceptor outer segment protein trafficking and survival.
PMID:33974130
Pathogenic STX3 variants affecting the retinal and intestinal transcripts cause an early-onset severe retinal dystrophy in microvillus inclusion disease subjects.
PMID:23132338
Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells.
PMID:39408994
Syntaxin 3B: A SNARE Protein Required for Vision.
file:human/STX3/STX3-uniprot.txt
UniProt record Q13277 (STX3_HUMAN)