GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:16169070
A human protein-protein interaction network: a resource for annotating the proteome.
PMID:16189514
Towards a proteome-scale map of the human protein-protein interaction network.
PMID:17224163
Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis.
PMID:19060904
An empirical framework for binary interactome mapping.
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:20458337
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
PMID:21653829
Protein interactome reveals converging molecular pathways among autism disorders.
PMID:21988832
Toward an understanding of the protein interaction network of the human liver.
PMID:2253271
Cloning and sequencing of a human cDNA coding for a multifunctional polypeptide of the purine pathway by complementation of the ade2-101 mutant in Saccharomyces cerevisiae.
PMID:23533145
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:25468996
E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
PMID:26871637
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PMID:27590927
CRISPR-Cas9 induced mutations along de novo purine synthesis in HeLa cells result in accumulation of individual enzyme substrates and affect purinosome formation.
PMID:31600779
PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome.
PMID:32296183
A reference map of the human binary protein interactome.
Reactome:R-HSA-73805
CAIR + Aspartate + ATP => SAICAR + ADP + Pi
Reactome:R-HSA-73806
AIR + CO2 => CAIR