Gene Ontology annotation through association of InterPro records with GO terms
TreeGrafter-generated GO annotations
Combined Automated Annotation using Multiple IEA Methods
UniProtKB reviewed entry for Pseudomonas putida KT2440 fadA
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UniProt identifies FadA as the cytoplasmic beta subunit of the FadBA heterotetramer and assigns the terminal beta-oxidation thiolase reaction.
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The PANTHER assignment is to the FadA-specific beta-oxidation subfamily rather than to the thiolase family root.
"PANTHER; PTHR43853:SF11; 3-KETOACYL-COA THIOLASE FADA; 1."
QuickGO annotation table for Pseudomonas putida KT2440 fadA
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GO:0010124 on Q88L01 is an unreviewed TreeGrafter inference whose only source is PANTHER:PTN002466592.
"GO:0010124 phenylacetate catabolic process biological_process ECO:0007826 IEA GO_REF:0000118 PANTHER:PTN002466592"
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The accepted GO:0006635 annotation draws on the same PANTHER node together with UniRule and UniPathway, confirming PTN002466592 is a beta-oxidation node.
"GO:0006635 fatty acid beta-oxidation biological_process ECO:0000501 IEA GO_REF:0000120 PANTHER:PTN002466592|UniRule:UR000080052|UniPathway:UPA00659"
QuickGO annotation table for Pseudomonas putida KT2440 paaJ
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paaJ, the thiolase of the dedicated phenylacetate route, carries GO:0010124 from a different PANTHER node than the one that placed the term on fadA.
"GO:0010124 phenylacetate catabolic process biological_process ECO:0007826 IEA GO_REF:0000118 PANTHER:PTN001291485"
Curation notes for Pseudomonas putida KT2440 fadA
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KT2440 catabolizes phenylacetate through a dedicated paa operon whose own thiolase paaJ is separately annotated, so GO:0010124 on fadA is thiolase-fold propagation rather than a FadA-specific role.
"KT2440 runs phenylacetate catabolism through a dedicated"
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paaJ receives the phenylacetate term from a different TreeGrafter node than the one that placed it on fadA, which corroborates but does not by itself establish the REMOVE.
"paaJ receives GO:0010124 from a different TreeGrafter node"
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GOA carries no cellular-component term for the FadBA complex on Q88L01, so the GO:0036125 part_of annotation fills a genuine gap.
"GOA carries no cellular-component term for this complex on Q88L01"