Gene Ontology annotation through association of InterPro records with GO terms.

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping.

PMID:14562095

Global analysis of protein localization in budding yeast.

Genome-wide GFP-fusion localization screen; ICY1 (Icy1p) is assigned to the vacuole (fungal-type vacuole) membrane in this dataset.

Suppression of a defect in mitochondrial protein import identifies cytosolic proteins required for viability of yeast cells lacking mitochondrial DNA.

Overexpression of ICY1 (with CCT6, SSB1, TIP41, PBP1) is a high-copy suppressor that rescues the mtDNA-dependence (petite-negative phenotype) of mitochondrial protein-import mutants; disruption of ICY1 produces cells unable to grow without mitochondrial DNA. ICY1 is described as a cytosolic protein.

PMID:12673624

Screening and characterization of transposon-insertion mutants in a pseudohyphal strain of Saccharomyces cerevisiae.

Transposon-insertion screen in a Sigma1278b pseudohyphal background; ICY1 disruption is associated with an invasive-growth defect and elongated cell morphology (UniProt DISRUPTION PHENOTYPE).

PMID:15843968

Transcriptional profiling of Saccharomyces cerevisiae cells under adhesion-inducing conditions.

Genome-wide expression profiling under amino-acid starvation (adhesion-inducing, Gcn4-linked conditions); ICY1 is among the genes induced by amino-acid starvation (UniProt INDUCTION).

PMID:26565778

Atg41/Icy2 regulates autophagosome formation.

Characterizes ICY1's whole-genome-duplication paralog ICY2, renamed ATG41, as an autophagosome-formation factor that interacts with Atg9. The full text reports that ICY1 has low sequence similarity to Atg41/Icy2 and that icy1 deletion, unlike icy2/atg41 deletion, does not impair autophagy.

PMID:25123508

The switch from fermentation to respiration in Saccharomyces cerevisiae is regulated by the Ert1 transcriptional activator/repressor.

Ert1 is a zinc-cluster transcriptional regulator of the fermentation-to-respiration switch; the paper's target-gene analysis (in supplementary tables not present in the cached text) lists ICY1 among Ert1 targets, linking ICY1 transcription to carbon-source/respiratory regulation.