Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Combined Automated Annotation using Multiple IEA Methods

UniProtKB entry Q9UBM7 (DHCR7_HUMAN)

Defining the membrane proteome of NK cells.

Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands.

The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally.

TMEM147 interacts with lamin B receptor, regulates its localization and levels, and affects cholesterol homeostasis.

7-Dehydrocholesterol is an endogenous suppressor of ferroptosis.

7-Dehydrocholesterol dictates ferroptosis sensitivity.

Molecular cloning and expression of the human delta7-sterol reductase.

The human lamin B receptor/sterol reductase multigene family.

Expression of 7-Dehydrocholesterol Reductase (DHCR7)

Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol

Cholesterol biosynthesis via desmosterol (Bloch pathway)

DHCR7 reduces 7-dehydroCHOL to CHOL

Cholesterol biosynthesis from zymosterol (modified Kandutsch-Russell pathway)