Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Protein-tyrosine phosphorylation interaction network in Bacillus subtilis reveals new substrates, kinase activators and kinase cross-talk
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MinD interacts with tyrosine kinase PtkA (ywqD) and acts as a scaffold protein anchoring PtkA at the cell pole
"MinD could act as a platform protein that would tether PtkA at a specific cellular area"
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MinD can activate PtkA autophosphorylation in vitro but less efficiently than TkmA
"Incubation of PtkA with increasing amounts of MinD activated its autophosphorylation"
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MinD is structurally homologous to BY-kinases but lacks kinase activity
"MinD is an ATPase from the P-loop NTPase superfamily previously reported to be a close structural homolog of BY-kinases, but lacking the C-terminal tyrosine cluster necessary for kinase autophosphorylation"
The MinCDJ system in Bacillus subtilis prevents minicell formation by promoting divisome disassembly.
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The B. subtilis MinCDJ system prevents polar division and promotes divisome disassembly after septation
"the main function of the Min system is to prevent minicell formation adjacent to recently completed division sites by promoting the disassembly of the cytokinetic ring"
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MinJ acts as bridge linking MinD/MinC to DivIVA
"a new component of the B. subtilis Min system was identified, MinJ, which acts as a bridge between DivIVA and MinCD"
Dynamics of the Bacillus subtilis Min System.
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MinD forms polar and septal enrichments rather than rapid pole-to-pole oscillation in B. subtilis
"the Min system of B. subtilis localizes dynamically to active sites of division, often organized in clusters"
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DivIVA senses negative membrane curvature and recruits MinJ which recruits MinC/MinD
"MinJ acts as a molecular bridge between MinD and DivIVA"
Septal membrane localization by C-terminal amphipathic α-helices of MinD in Bacillus subtilis mutant cells lacking MinJ or DivIVA.
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B. subtilis MinD has two C-terminal amphipathic helices (MTS1 and MTSL) for membrane targeting
"Bacillus subtilis MinD has two amphipathic α-helices rich in basic amino acid residues at its C-terminus"
MinJ (YvjD) is a topological determinant of cell division in Bacillus subtilis.
A novel component of the division-site selection system of Bacillus subtilis and a new mode of action for the division inhibitor MinCD