Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Splicing mutations of 54-bp exons in the COL11A1 gene cause Marshall syndrome, but other mutations cause overlapping Marshall/Stickler phenotypes.
An amino acid substitution (Gly853-->Glu) in the collagen alpha 1(II) chain produces hypochondrogenesis.
High efficiency of mutation detection in type 1 stickler syndrome using a two-stage approach: vitreoretinal assessment coupled with exon sequencing for screening COL2A1.
The collagen family members as cell adhesion proteins.
Nonmuscle myosin-dependent synthesis of type I collagen.
Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.
Molecular properties and fibril ultrastructure of types II and XI collagens in cartilage of mice expressing exclusively the α1(IIA) collagen isoform.
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Comprehensive proteomic characterization of stem cell-derived extracellular matrices.
Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.
COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dominant mutations in the type II collagen gene, COL2A1, produce spondyloepimetaphyseal dysplasia, Strudwick type.
Structural analysis of cross-linking domains in cartilage type XI collagen. Insights on polymeric assembly.
A COL2A1 mutation in achondrogenesis type II results in the replacement of type II collagen by type I and III collagens in cartilage.
Collagen type IX from human cartilage: a structural profile of intermolecular cross-linking sites.
Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB).
X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II.
Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13
Collagen type II degradation by MMP1,3,8,13,PRSS2
Formation of collagen fibrils
Removal of fibrillar collagen N-propeptides
Removal of fibrillar collagen C-propeptides
Procollagen triple helix formation
Collagen type II binds integrin alpha10beta1
Formation of collagen fibres
Type XII and XIV collagens associate with type I and type II fibrils
Type X collagen associates with collagen type II fibrils
Collagen IX is cross-linked to the surface of collagen type II fibrils
Collagen XI cross-links with collagen II
FN1 binds Collagen types I-V, VII
DDR1 binds collagen type I, II, III, IV, V, XI fibrils
DCN binds collagen I, II, III, VI fibrils
VTN binds collagens II, III and V
COMP binds collagen, fibronectin, aggrecan and matrilins
DDR2 binds collagen type I, II, III, V, X fibrils
Collagen type II degradation by MMP15
Interaction of NCAM1 with collagens
PDGF binds to extracellular matrix proteins
OSCAR binds collagen and SP-D
Association of procollagen type II
Association of procollagen type XI
SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse.
The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9.
Chondrogenic differentiation during midfacial development in the mouse: in vivo and in vitro studies.
Protein consequences of the Col2a1 C-propeptide mutation in the chondrodysplastic Dmm mouse.
Age-dependent changes in the expression of matrix components in the mouse eye.
Disruption of the developmentally-regulated Col2a1 pre-mRNA alternative splicing switch in a transgenic knock-in mouse model.
Collagen II is essential for the removal of the notochord and the formation of intervertebral discs.
Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesis.
Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.