GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11001923
Interaction between LIS1 and doublecortin, two lissencephaly gene products.
PMID:14741102
Doublecortin microtubule affinity is regulated by a balance of kinase and phosphatase activity at the leading edge of migrating neurons.
PMID:21044950
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
PMID:21516116
Next-generation sequencing to generate interactome datasets.
PMID:24607389
Mutations in USP9X are associated with X-linked intellectual disability and disrupt neuronal cell migration and growth.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:27292316
A novel DCX missense mutation in a family with X-linked lissencephaly and subcortical band heterotopia syndrome inherited from a low-level somatic mosaic mother: Genetic and functional studies.
PMID:31515488
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:9489699
A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome.
Reactome:R-NUL-443772
Doublecortin binds phosphorylated neurofascin
PMID:10399933
Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons.
PMID:10399932
Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons.
PMID:15200960
Mechanism of microtubule stabilization by doublecortin.
PMID:22727374
Doublecortin recognizes the 13-protofilament microtubule cooperatively and tracks microtubule ends.
PMID:14625554
RNAi reveals doublecortin is required for radial migration in rat neocortex.
PMID:27238282
Doublecortin Is Excluded from Growing Microtubule Ends and Recognizes the GDP-Microtubule Lattice.
PMID:15173193
Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration.
file:human/DCX/DCX-deep-research-falcon.md
Falcon deep research report for DCX
file:human/DCX/DCX-uniprot.txt
UniProtKB record for human DCX (O43602)
file:human/DCX/DCX-notes.md
DCX review notes