Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5.

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes.

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling.

Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis.

Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity.

Plasma cytokine concentrations associated with HIV/hepatitis C coinfection are related to attention, executive and psychomotor functioning.

Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway.

Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis.

Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL- and CD95-mediated apoptosis of glioblastoma cells.

Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP.

Inhibition of vacuolar ATPase attenuates the TRAIL-induced activation of caspase-8 and modulates the trafficking of TRAIL receptosomes.

The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex.

A physical wiring diagram for the human immune system.

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.

Identification and characterization of a new member of the TNF family that induces apoptosis.

TRAIL/Apo-2-ligand-induced apoptosis in human T cells.

Caspase-8 processing in the DISC

Trimerization of TRAIL:TRAIL receptor complex

TRAIL-mediated dimerization of procaspase-8

TRAIL:TRAIL-Receptor2 Trimer:FADD complex binds procaspase-10

FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling

FLIP(S) and procaspase-8 form heterodimer

Caspase-8 and FLIP(L) processing at DISC

FLIP(L) and procaspase-8 form heterodimer

TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8

TRAIL:TRAIL receptor trimers bind FADD

TRAIL binds TRAIL receptors