Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
The complex of Arl2-GTP and PDE delta: from structure to function.
A human protein-protein interaction network: a resource for annotating the proteome.
Towards a proteome-scale map of the human protein-protein interaction network.
Deletion of PrBP/delta impedes transport of GRK1 and PDE6 catalytic subunits to photoreceptor outer segments.
Specificity of Arl2/Arl3 signaling is mediated by a ternary Arl3-effector-GAP complex.
Next-generation sequencing to generate interactome datasets.
The interplay between RPGR, PDEδ and Arl2/3 regulate the ciliary targeting of farnesylated cargo.
A proteome-scale map of the human interactome network.
The EHEC-host interactome reveals novel targets for the translocated intimin receptor.
The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function.
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Architecture of the human interactome defines protein communities and disease networks.
Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Characterization of human and mouse rod cGMP phosphodiesterase delta subunit (PDE6D) and chromosomal localization of the human gene.
The rod cGMP phosphodiesterase delta subunit dissociates the small GTPase Rab13 from membranes.
The retinitis pigmentosa GTPase regulator, RPGR, interacts with the delta subunit of rod cyclic GMP phosphodiesterase.
INPP5E translocates to the primary cilium
PDE6D dissociates from ARL13B:INPP5E
ARL2:GTP bind PDE6D on KRAS4B
PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+
KRAS4B recycles to the plasma membrane
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo.
Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling.
A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium.
Falcon deep research report for PDE6D (human)