GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:10369267
A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy.
PMID:12620389
Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis.
PMID:16189514
Towards a proteome-scale map of the human protein-protein interaction network.
PMID:16502470
Human colostrum: identification of minor proteins in the aqueous phase by proteomics.
PMID:16713569
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
PMID:18985028
Hepatitis C virus infection protein network.
PMID:19275936
ECM1 interacts with fibulin-3 and the beta 3 chain of laminin 332 through its serum albumin subdomain-like 2 domain.
PMID:19804359
EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells.
PMID:20005202
Fibulin-3 negatively regulates chondrocyte differentiation.
PMID:20551380
Proteomics characterization of extracellular space components in the human aorta.
PMID:21653829
Protein interactome reveals converging molecular pathways among autism disorders.
PMID:23533145
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
PMID:23962539
Elastic fibres in health and disease.
PMID:25037231
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.
PMID:25406291
Human eye development is characterized by coordinated expression of fibrillin isoforms.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:25910212
Widespread macromolecular interaction perturbations in human genetic disorders.
PMID:26871637
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PMID:27068509
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
PMID:28675934
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
PMID:31515488
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:32814053
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
PMID:35998264
A loss-of-function cysteine mutant in fibulin-3 (EFEMP1) forms aberrant extracellular disulfide-linked homodimers and alters extracellular matrix composition.
PMID:36399478
MatrisomeDB 2.0: 2023 updates to the ECM-protein knowledge database.
Reactome:R-HSA-1592387
Fibulin binds elastic fibres
Reactome:R-HSA-2161282
Elastic fibres bind associated proteins
PMID:10601734
Sequence, recombinant expression and tissue localization of two novel extracellular matrix proteins, fibulin-3 and fibulin-4.
PMID:15123717
Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1). Implications for macular degenerations.