Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Identification of a novel family of ankyrin repeats containing cofactors for p160 nuclear receptor coactivators.
Mutations in ANKRD11 cause KBG syndrome, characterized by intellectual disability, skeletal malformations, and macrodontia.
Characterization of ANKRD11 mutations in humans and mice related to KBG syndrome.
Ankrd11 is a chromatin regulator involved in autism that is essential for neural development.
Characterization of transcriptional regulatory domains of ankyrin repeat cofactor-1.
Identification of ANKRD11 as a p53 coactivator.
ANKRD11 binding to cohesin suggests a connection between KBG syndrome and Cornelia de Lange syndrome.
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A human ANKRD11 peptide directly binds the cohesin STAG2–RAD21 interface and competes with CTCF; downstream endogenous perturbation experiments use mouse cells.
"ANKRD11 effectively outcompeted CTCF in binding"
UniProtKB Q6UB99: Ankyrin repeat domain-containing protein 11
Human Protein Atlas: ANKRD11 subcellular localization