Source: pre-release post-processed-2026_02_28k.xml, accession O13993. The exact entry is preserved in rpo41-protnlm-source.xml; all original evidence elements and model scores are retained in rpo41-protnlm-source.json. This record is currently Swiss-Prot and is absent from the published 26,856-record TrEMBL pilot list. The current public ProtNLM endpoint returns this record; API availability is distinct from membership in the published pilot list. No training-membership inference is made.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Original evidence key(s): 2.
| Atomic claim | Assessment | Evidence and limit |
|---|---|---|
| DNA-dependent RNA synthesis | CNN | Purified fission-yeast Rpo41 transcribes DNA templates. The target is the catalytic single-subunit mitochondrial polymerase, unlike an accessory Pol I subunit. |
| Use of the four ribonucleoside triphosphates | CNN | The reconstituted transcription reaction uses ATP, CTP, GTP and UTP. This is established polymerase chemistry, not a new function. |
publications/PMID_21357609.md).Family and feature provenance: rpo41-uniprot.txt.
Decisive excerpt, PMID:21357609: “We show biochemically, that purified Mtf1 and Rpo41 together can bind to the S. pombe mitochondrial promoters and can support transcription from the S. pombe mitochondrial promoters in vitro.”