Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture.
Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases.
Blood monocytes: development, heterogeneity, and relationship with dendritic cells.
Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells.
Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood.
Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles.
Structural basis for the dual recognition of helical cytokines IL-34 and CSF-1 by CSF-1R.
Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1.
Regulation of microglial proliferation during chronic neurodegeneration.
Human IL-34 and CSF-1 establish structurally similar extracellular assemblies with their common hematopoietic receptor.
Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus.
Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1.
miR-28-5p-IL-34-macrophage feedback loop modulates hepatocellular carcinoma metastasis.
Interleukin-34, a comprehensive review.
Physical and functional interactome atlas of human receptor tyrosine kinases.
A physical wiring diagram for the human immune system.
Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor.
Expression of human colony-stimulating factor-1 (CSF-1) receptor in murine pluripotent hematopoietic NFS-60 cells induces long-term proliferation in response to CSF-1 without loss of erythroid differentiation potential.
Colony stimulating factor-1 potentiates neuronal survival in cerebral cortex ischemic lesion.
Biology and action of colony--stimulating factor-1.
VENTX stimulates CSF1R (M-CSF-R) expression
IL34 dimer:SDC1 binds CSF1R
Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects.
Discovery of a cytokine and its receptor by functional screening of the extracellular proteome.
IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation.
Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids.
Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia.
Bi-allelic CSF1R Mutations Cause Skeletal Dysplasia of Dysosteosclerosis-Pyle Disease Spectrum and Degenerative Encephalopathy with Brain Malformation.
The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation.
Insulin-like growth factor 2 receptor is an IFNgamma-inducible microglial protein that facilitates intracellular HIV replication: implications for HIV-induced neurocognitive disorders.
T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation.
Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation.
UniProtKB P07333 (CSF1R_HUMAN) entry
Falcon (Edison) deep research report on CSF1R
A novel role for protein tyrosine phosphatase shp1 in controlling glial activation in the normal and injured nervous system.
A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model.
Evidence for cFMS signaling in HIV production by brain macrophages and microglia.
CSF1R source identity, propagation and assay evidence