Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.
EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.
FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.
Defining the membrane proteome of NK cells.
The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.
DNA polymerase POLN participates in cross-link repair and homologous recombination.
FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL.
DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI.
FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5'-DNA end.
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2.
CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.
DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex
Monoubiquitination of FANCD2:FANCI
DNA nucleases bind monoubiquitinated ID2 complex
DNA nucleases unhook the interstrand crosslink (ICL)
Translesion synthesis across unhooked ICL by POLN
FANCD2 deubiquitination by USP1:WDR48
The complex of ATR and ATRIP is recruited to ICL-DNA
ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA
CDK12 stimulates expression of DNA repair genes