The review YAML contains the final 34 annotation decisions and 15 reference assessments. Its single molecular-function core is CDC42 nucleotide exchange through the DH–PH region, with cytosolic and plasma-membrane-associated pools. Actin organization, filopodial responses and cell shape remain downstream contextual effects rather than separate structural or actin-binding molecular functions.
The literature journal, direct source guide and database source guide identify the actual original Methods, Results, captions and database records read. The review preserves all imported source objects and reference identities/findings; it adds one independently verified mouse-donor reference. It introduces no NEW annotation, natural product or publication quotation, in accordance with the campaign instructions.
All 19 accepted source files remain preserved privately. The installation subset is ten files: three publications, four Reactome entries and three unchanged PANTHER/PAINT records. The other nine discovery sources are unused. The final decisions are 11 ACCEPT, 14 KEEP_AS_NON_CORE, six TOO_GENERAL, two MODIFY and one UNDECIDED. The two replacements preserve CDC42-specific signaling regulation (GO:0032489) and exchange-defined GTPase activation (GO:0090630). The single core process also uses GO:0032489. Current definitions and typed hierarchy evidence are recorded in the ontology sidecar.