file:human/DHODH/DHODH-uniprot.txt
UniProtKB Q02127 (PYRD_HUMAN) - Dihydroorotate dehydrogenase (quinone), mitochondrial
GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000043
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:8925840
Functional expression of a fragment of human dihydroorotate dehydrogenase by means of the baculovirus expression vector system, and kinetic investigation of the purified recombinant enzyme.
PMID:10673429
Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:34800366
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Reactome:R-HSA-73569
DHODH:FMN oxidises (S)-DHO to orotate
Reactome:R-HSA-9708759
DHODH:FMN binds DHODH inhibitors
PMID:33981038
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer.
file:human/DHODH/DHODH-deep-research-falcon.md
Deep research report on human DHODH gene function
PMID:10727948
Requirements for the mitochondrial import and localization of dihydroorotate dehydrogenase.
PMID:27485036
Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation.
PMID:30449682
Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.
PMID:6249586
On the role of dihydroorotate dehydrogenase in growth cessation of Ehrlich ascites tumor cells cultured under oxygen deficiency.
PMID:37407687
DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition.
PMID:37407682
Reply to: DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition.
PMID:34341547
Author Correction: DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer.
PMID:19915526
Exome sequencing identifies the cause of a mendelian disorder.
file:human/DHODH/DHODH-evidence-guide.md
DHODH source evidence and assay-scope guide