Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans.
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ZIP-2 identified as transcription factor required for irg-1 induction
"bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans."
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zip-2 knockdown decreases survival upon P. aeruginosa infection
"bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans."
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ZIP-2 is part of specialized pathogen response pathway
"bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans."
Host translational inhibition by Pseudomonas aeruginosa Exotoxin A triggers an immune response in Caenorhabditis elegans.
C. elegans detects pathogen-induced translational inhibition to activate immune signaling.
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ZIP-2 activated by translational inhibition
"C. elegans detects pathogen-induced translational inhibition to activate immune signaling."
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Nuclear localization demonstrated
"C. elegans detects pathogen-induced translational inhibition to activate immune signaling."
Networks of bZIP protein-protein interactions diversified over a billion years of evolution.
Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network.
Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection.
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zip-2 induced during mitochondrial stress in atfs-1-dependent manner
"Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection."
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ZIP-2 required for irg-1 induction during UPRmt
"Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection."
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Genetic interaction with atfs-1 in defense against P. aeruginosa
"Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection."
The C. elegans CCAAT-Enhancer-Binding Protein Gamma Is Required for Surveillance Immunity.
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CEBP-2 acts together with ZIP-2 in surveillance immunity
"The C. elegans CCAAT-Enhancer-Binding Protein Gamma Is Required for Surveillance Immunity."
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Both required for protective response to translational block
"The C. elegans CCAAT-Enhancer-Binding Protein Gamma Is Required for Surveillance Immunity."
A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa.
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ZIP-2 is part of bZIP family mediating ESRE network
"A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa."
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Loss of zip-2 compromises ESRE gene induction
"A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa."
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zip-2 mutants sensitive to Liquid Killing
"A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa."
A cellular surveillance and defense system that delays aging phenotypes in C. elegans.
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zip-2 involved in response to mitochondrial damage
"A cellular surveillance and defense system that delays aging phenotypes in C. elegans."
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Role in delaying age-associated mitochondrial fragmentation
"A cellular surveillance and defense system that delays aging phenotypes in C. elegans."
Deep research report on zip-2