Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Myosins: a diverse superfamily.
Familial hypertrophic cardiomyopathy mutations in the regulatory light chains of myosin affect their structure, Ca2+ binding, and phosphorylation.
Protein interactions with myocilin.
Identification of novel VHL target genes and relationship to hypoxic response pathways.
The Tre2 oncoprotein, implicated in Ewing's sarcoma, interacts with two components of the cytoskeleton.
Structure and function of myosin filaments.
Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study.
Endosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassembly.
A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart.
Recessive MYL2 mutations cause infantile type I muscle fibre disease and cardiomyopathy.
A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis.
A reference map of the human binary protein interactome.
Novel frameshift variant in MYL2 reveals molecular differences between dominant and recessive forms of hypertrophic cardiomyopathy.
Interaction of a conserved peptide domain in recombinant human ventricular myosin light chain-2 with myosin heavy chain.
Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle.
Different actin affinities of human cardiac essential myosin light chain isoforms.
Release Of ADP From Myosin
Selective requirement of myosin light chain 2v in embryonic heart function.
Acceleration of stretch activation in murine myocardium due to phosphorylation of myosin regulatory light chain.
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MLCK phosphorylation of RLC increases the calcium sensitivity of isometric force in mouse myocardium.
"MLCK increased RLC phosphorylation, increased the Ca(2+) sensitivity of isometric force"
Abnormal cardiac structure and function in mice expressing nonphosphorylatable cardiac regulatory myosin light chain 2.
Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene.
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The MLC-2v gene is expressed exclusively in the ventricular compartment of the heart.
"both the endogenous MLC-2 gene and the MLC-2 luciferase fusion gene were expressed exclusively in the ventricular compartment"
UniProtKB P10916: human MYL2 curated entry