GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:18004775
Human uroporphyrinogen III synthase: NMR-based mapping of the active site.
PMID:18936296
Structural insight into acute intermittent porphyria.
PMID:19138865
Correlation between biochemical findings, structural and enzymatic abnormalities in mutated HMBS identified in six Israeli families with acute intermittent porphyria.
PMID:2025226
Studies on the mechanism of hydroxymethylbilane synthase concerning the role of arginine residues in substrate binding.
PMID:23815679
Conformational stability and activity analysis of two hydroxymethylbilane synthase mutants, K132N and V215E, with different phenotypic association with acute intermittent porphyria.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:32814053
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Reactome:R-HSA-189406
4 PBGs bind to form HMB
Reactome:R-HSA-189451
Heme biosynthesis
file:human/HMBS/HMBS-uniprot.txt
UniProtKB entry P08397 (HEM3_HUMAN) - HMBS / porphobilinogen deaminase