PMID:24239007

The end of an old hypothesis: the pseudomonas signaling molecules 4-hydroxy-2-alkylquinolines derive from fatty acids, not 3-ketofatty acids.

PqsB is tightly associated with PqsC and required for the condensation step; the octanoate group is carried on PqsC.

"the decarboxylating coupling of 2-ABA to an octanoate group linked to PqsC produces HHQ, the direct precursor of PQS. PqsB is tightly associated with PqsC and required for the second step."

PMID:26811339

PqsBC, a Condensing Enzyme in the Biosynthesis of the Pseudomonas aeruginosa Quinolone Signal: CRYSTAL STRUCTURE, INHIBITION, AND REACTION MECHANISM.

PqsBC has a unique heterodimeric arrangement; the catalytic active site (Cys-129, His-269) lies in PqsC, so PqsB is the non-catalytic subunit.

"does not form a catalytic triad with His-269 and Cys-129, and in its place a valine (Val-299) is present"

PMID:12426334

Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa.

The pqsABCDE operon (including pqsB) is required for synthesis of the extracellular Pseudomonas quinolone signal.

"Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa"

file:PSEAE/pqsB/pqsB-notes.md

pqsB review notes (BGC project) with predicted-complex evidence

GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

GO_REF:0000044

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping