Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference

Combined Automated Annotation using Multiple IEA Methods

Inactivation of homocitrate synthase causes lysine auxotrophy in copper/zinc-containing superoxide dismutase-deficient yeast Schizosaccharomyces pombe.

Six new amino acid-auxotrophic markers for targeted gene integration and disruption in fission yeast.

Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis.

Structural basis for L-lysine feedback inhibition of homocitrate synthase.

Lysine biosynthesis pathway and biochemical blocks of lysine auxotrophs of Schizosaccharomyces pombe.