Gene Ontology annotation through association of InterPro records with GO terms
Combined Automated Annotation using Multiple IEA Methods
Fusarium graminearum gene deletion mutants map1 and tri5 reveal similarities and differences in the pathogenicity requirements to cause disease on Arabidopsis and wheat floral tissue.
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PH-1 tri5 deletion abolishes DON production and restricts wheat-ear disease to inoculated spikelets, but not disease on Arabidopsis floral tissue.
"This study reveals that DON mycotoxin production is not required for F. graminearum to colonize Arabidopsis floral tissue."
Reduced virulence of Gibberella zeae caused by disruption of a trichothecene toxin biosynthetic gene.
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Tri5 encodes trichodiene synthase, the first enzyme of trichothecene biosynthesis; Tri5- strains have host-dependent reduced virulence.
"These results suggest that trichothecene production contributes to the virulence of G. zeae on some hosts."
Expression of the Fusarium graminearum terpenome and involvement of the endoplasmic reticulum-derived toxisome.
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Recombinant TRI5 produces mainly trichodiene; TRI5 protein, independent of catalysis, is required for toxisome formation and non-trichothecene sesquiterpene synthesis.
"Our results indicate that the Tri5 protein, but not its enzymatic activity, is also required for the synthesis of non-trichothecene related sesquiterpenes and the formation of toxisomes."
Involvement of trichothecenes in fusarioses of wheat, barley and maize evaluated by gene disruption of the trichodiene synthase (Tri5) gene in three field isolates of different chemotype and virulence.
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Tri5 disruption mutants fail to spread beyond inoculated wheat spikelets; the contribution of trichothecenes to virulence is host- and chemotype-dependent.
"all disruption mutants caused disease symptoms on the inoculated spikelet, but the symptoms did not spread into other spikelets."
Fusarium graminearum forms mycotoxin producing infection structures on wheat.
The trichothecene mycotoxin deoxynivalenol facilitates cell-to-cell invasion during wheat-tissue colonization by Fusarium graminearum.
Deep research report on TRI5 (falcon)