Use of the ND evidence code for Gene Ontology (GO) terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

PMID:14562095

Global analysis of protein localization in budding yeast.

PMID:15145942

COX23, a homologue of COX17, is required for cytochrome oxidase assembly.

PMID:19703468

Systematic analysis of the twin cx(9)c protein family.

PMID:22984289

Intermembrane space proteome of yeast mitochondria.

PMID:28357365

Cox1 mutation abrogates need for Cox23 in cytochrome c oxidase biogenesis.

DOI:10.1038/s41467-026-77112-z

The predicted interactome of the human mitochondrial proteome.

AlphaFold-Multimer predicted evolutionarily conserved COX23-COX1, CMC2-COX2 and COA4-COX11 interactions among poorly characterized complex IV assembly factors. The COX23-COX1 and CMC2-COX2 contacts were not experimentally followed up in that paper, while the COA4-COX11 prediction was prioritized for crosslinking and co-immunoprecipitation.

"AFM predicted evolutionarily conserved interactions between COX23 and COX1, CMC2 with COX2, and COA4 with COX11"

file:yeast/COX23/COX23-notes.md

yeast/COX23/COX23-notes.md