Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Combined Automated Annotation using Multiple IEA Methods
The deubiquitinating enzyme USP10 regulates the post-endocytic sorting of cystic fibrosis transmembrane conductance regulator in airway epithelial cells.
Defining the human deubiquitinating enzyme interaction landscape.
USP10 regulates p53 localization and stability by deubiquitinating p53.
A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system.
Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Both G3BP1 and G3BP2 contribute to stress granule formation.
USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO.
Deubiquitination and stabilization of T-bet by USP10.
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.
A proteome-scale map of the human interactome network.
TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase.
G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
The G3BP1-Family-USP10 Deubiquitinase Complex Rescues Ubiquitinated 40S Subunits of Ribosomes Stalled in Translation from Lysosomal Degradation.
Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized.
A reference map of the human binary protein interactome.
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
The E3 ubiquitin ligase RNF10 modifies 40S ribosomal subunits of ribosomes compromised in translation.
iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation.
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.
SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.
CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Differential CFTR-Interactome Proximity Labeling Procedures Identify Enrichment in Multiple SLC Transporters.
Yin and yang regulation of stress granules by Caprin-1.
Immune evasion strategy involving propionylation by the KSHV interferon regulatory factor 1 (vIRF1).
MAVS-loaded unanchored Lys63-linked polyubiquitin chains activate the RIG-I-MAVS signaling cascade.
Multimodal cell maps as a foundation for structural and functional genomics.
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template
USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA
USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA
USP10,USP24,USP42 deubiquitinate TP53
USP13 deubiquitinates BECN1,USP10
USP10 deubiquitinates SNX3, CFTR
The ubiquitin isopeptidase USP10 deubiquitinates LC3B to increase LC3B levels and autophagic activity.