Transmembrane topology of human glucose 6-phosphate transporter.
Glucose-6-phosphatase mutation G188R confers an atypical glycogen storage disease type 1b phenotype.
The catalytic center of glucose-6-phosphatase. HIS176 is the nucleophile forming the phosphohistidine-enzyme intermediate during catalysis.
Glycogen storage disease type Ia in Argentina: two novel glucose-6-phosphatase mutations affecting protein stability.
Brain contains a functional glucose-6-phosphatase complex capable of endogenous glucose production.
Mutations in the glucose-6-phosphatase gene that cause glycogen storage disease type 1a.
Glycogen storage disease type 1a in Israel: biochemical, clinical, and mutational studies.
Transmembrane topology of glucose-6-phosphatase.
Structural insights into glucose-6-phosphate recognition and hydrolysis by human G6PC1.
Isolation of the gene for murine glucose-6-phosphatase, the enzyme deficient in glycogen storage disease type 1A.
Gossypol ameliorates liver fibrosis in diabetic rats induced by high-fat diet and streptozocin.
Fasting for 3 days during the suckling-weaning transient period in male rats induces metabolic abnormalities in the liver and is associated with impaired glucose tolerance in adulthood.
An acute increase in fructose concentration increases hepatic glucose-6-phosphatase mRNA via mechanisms that are independent of glycogen synthase kinase-3 in rats.
Liver glyconeogenesis: a pathway to cope with postprandial amino acid excess in high-protein fed rats?
Resveratrol improves glycemic control in insulin-treated diabetic rats: participation of the hepatic territory.
Regulation of glucose-6-phosphatase gene expression by insulin and metformin.
Gluconeogenesis in developing rat kidney cortex.
Perturbation of fuel homeostasis caused by overexpression of the glucose-6-phosphatase catalytic subunit in liver of normal rats.
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Defective G6PC does not hydrolyze glucose 6-phosphate
G6PC hydrolyzes G6P to Glc and Pi (liver)
TCF19:NuRD represses G6PC gene expression
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.