GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
PMID:1373518
CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes.
PMID:1383329
The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules.
PMID:16672701
An antibody-deficiency syndrome due to mutations in the CD19 gene.
PMID:1702139
Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19.
PMID:17213291
FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection.
PMID:20458337
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
PMID:20660734
MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output.
PMID:23071339
Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros.
PMID:2463100
Regulatory role of CD19 molecules in B-cell activation and differentiation.
PMID:29523808
Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells.
PMID:9317126
Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu 13 complex requires the cytoplasmic domain of CD19.
PMID:9382888
Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization.
Reactome:R-HSA-199518
C3d-complexed antigen binds to complement receptor
Reactome:R-HSA-2076220
CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3
Reactome:R-HSA-2316434
PI3K phosphorylates PIP2 to PIP3
Reactome:R-HSA-2400009
PI3K inhibitors block PI3K catalytic activity
Reactome:R-HSA-8853252
CR2:C3d,C3dg,iC3b binds CD19:CD81
Reactome:R-HSA-9606887
p-CD19:VAV binds PI3K and GRB2