GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:10024875
Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor.
PMID:17897319
Integral and associated lysosomal membrane proteins.
PMID:19116314
Localization to mature melanosomes by virtue of cytoplasmic dileucine motifs is required for human OCA2 function.
PMID:22511774
BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organelles.
PMID:23247405
Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:28514442
Architecture of the human interactome defines protein communities and disease networks.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:32814053
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:40355756
The solute carrier superfamily interactome.
PMID:9151686
Characterization of the adaptor-related protein complex, AP-3.
PMID:9545220
Association of the AP-3 adaptor complex with clathrin.
PMID:9118953
AP-3: an adaptor-like protein complex with ubiquitous expression.
PMID:9748267
The medium subunits of adaptor complexes recognize distinct but overlapping sets of tyrosine-based sorting signals.
PMID:9794796
Specificity of interaction between adaptor-complex medium chains and the tyrosine-based sorting motifs of TGN38 and lgp120.
PMID:11071885
Multiple C-terminal motifs of the 46-kDa mannose 6-phosphate receptor tail contribute to efficient binding of medium chains of AP-2 and AP-3.
PMID:39705307
A structure-based mechanism for initiation of AP-3 coated vesicle formation.
PMID:42139345
Architecture of clathrin-independent AP3:ARF1-coated carriers.
PMID:34688652
Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
PMID:29028839
Interaction of the Human Respiratory Syncytial Virus matrix protein with cellular adaptor protein complex 3 plays a critical role in trafficking.
PMID:21998198
The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse.
PMID:27568566
Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway.
PMID:15537701
Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain.
PMID:19010779
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.
PMID:29032074
Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer.
PMID:14575525
Genomic organization and linkage via a bidirectional promoter of the AP-3 (adaptor protein-3) mu3A and AK (adenosine kinase) genes: deletion mutants of AK in Chinese hamster cells extend into the AP-3 mu3A gene.
PMID:31898847
Hermansky-Pudlak syndrome: Mutation update.
PMID:8918456
Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes.
file:human/AP3M1/AP3M1-uniprot.txt
UniProtKB Q9Y2T2 (AP3M1_HUMAN) flat file
file:human/AP3M1/AP3M1-bioinformatics/RESULTS.md
AP3M1 bioinformatics: the YxxPhi cargo pocket of the AP-3 mu subunit
file:human/AP3M1/AP3M1-deep-research-affinage.md
Affinage mechanistic annotation for AP3M1 (human)