GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000113
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10625658
Both PCE-1/RX and OTX/CRX interactions are necessary for photoreceptor-specific gene expression.
PMID:10887186
The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation.
PMID:16189514
Towards a proteome-scale map of the human protein-protein interaction network.
PMID:22458338
Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses.
PMID:24722188
Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:25910212
Widespread macromolecular interaction perturbations in human genetic disorders.
PMID:26871637
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PMID:28473536
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
PMID:29892012
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.
PMID:31515488
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:9390563
Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor.
PMID:41418782
Human CRX regulates photoreceptor cells development via bidirectional transcriptional control in retinal organoids.
PMID:12408971
Characterization of the genomic and transcriptional structure of the CRX gene: substantial differences between human and mouse.
PMID:18854042
FIZ1 is part of the regulatory protein complex on active photoreceptor-specific gene promoters in vivo.
PMID:14613968
Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.
PMID:16574740
Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta.
PMID:15689355
The photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genes.