Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Dissection of epistasis in oligogenic Bardet-Biedl syndrome.
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.
Retinal morphology in patients with BBS1 and BBS10 related Bardet-Biedl Syndrome evaluated by Fourier-domain optical coherence tomography.
Novel interaction partners of Bardet-Biedl syndrome proteins.
Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses.
A BBSome subunit links ciliogenesis, microtubule stability, and acetylation.
Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling.
BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia.
Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes.
BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes.
Direct role of Bardet-Biedl syndrome proteins in transcriptional regulation.
Intrinsic protein-protein interaction-mediated and chaperonin-assisted sequential assembly of stable bardet-biedl syndrome protein complex, the BBSome.
BBS mutations modify phenotypic expression of CEP290-related ciliopathies.
The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome.
Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein.
Structural basis for membrane targeting of the BBSome by ARL6.
Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Protein interaction perturbation profiling at amino-acid resolution.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Multimodal cell maps as a foundation for structural and functional genomics.
ARL6:GTP and the BBSome bind ciliary cargo
ARL6:GTP and the BBSome target cargo to the primary cilium
LZTFL1 binds the BBSome and prevents its traffic to the cilium