Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal.

Formation and biochemical characterization of tube/pelle death domain complexes: critical regulators of postreceptor signaling by the Drosophila toll receptor.

Three-dimensional structure of a complex between the death domains of Pelle and Tube.

Fly immunity: great expectations.

Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections.

A heterotrimeric death domain complex in Toll signaling.

Sequential activation of signaling pathways during innate immune responses in Drosophila.

Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo.

Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis.

Phosphoinositide binding by the Toll adaptor dMyD88 controls antibacterial responses in Drosophila.

Next-generation Drosophila protein interactome map and its functional implications.

Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos.

Genetic characterization of tube and pelle, genes required for signaling between Toll and dorsal in the specification of the dorsal-ventral pattern of the Drosophila embryo.

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults.

An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators.

The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo.

Activated PLL kinase is autophosphorylated in TL:MYD88:TUB:PLL 'signalling complex'

PLL kinase binds to TL:MYD88:TUB 'signalling complex'

MYD88:TUB binds to TL receptor

MYD88 binds to TUB

CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex'

Phosphorylated CACT and DL dimer dissociate from the TL:WEK:MYD88:TUB:PLL 'signalling complex'

WEK and MYD88:TUB bind to the TL receptor

DL/DIF dimer binds to TUB and phosphorylated PLL in TL:MYD88:TUB:PLL 'signalling complex'

Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex'

CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex'

Phosphorylated CACT and DL/DIF dimer dissociate from the TL:MYD88:TUB:PLL 'signalling complex'

PLL kinase binds to TL:WEK:MYD88:TUB 'signalling complex'

DL dimer binds to TUB and phosphorylated PLL in TL:WEK:MYD88:TUB:PLL 'signalling complex'

Falcon deep research report for tub

Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity.

UniProt entry P22812 (tub)

FlyBase gene description for tub (DROME)