erg11 (SPAC13A11.02c, UniProt Q09736) notes
Module: ergosterol_biosynthesis (CYP51); S. cerevisiae ortholog ERG11 (P10614). Fetch verified: Q09736 (CP51_SCHPO).
Naming: UniProt mentions "erg11/cyp1"; the protein is CYP51 (Cyp51A1 in Hughes et al. 2007).
Evidence
Curation decisions
- protein binding (Dap1) REMOVE as uninformative; interaction not disputed.
- monooxygenase / paired-donor oxidoreductase IEA MODIFY -> GO:0008398; membrane -> ER membrane.
- UniProt PANTHER xref is PTHR24304:SF2 (labelled 24-hydroxycholesterol 7-alpha-hydroxylase) - a PANTHER labelling quirk worth noting for the module's CYP51 family descriptor.