Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
TreeGrafter-generated GO annotations
Combined Automated Annotation using Multiple IEA Methods
A putative polyketide synthase/peptide synthetase from Magnaporthe grisea signals pathogen attack to resistant rice.
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A functional Ace1-GFP fusion is restricted to the cytoplasm of appressoria and is not secreted, and a KS active-site C183A mutant loses avirulence on Pi33 rice, so ACE1 enzymatic activity is required for avirulence.
"These results demonstrate that the ace1 C183A : GFP allele is unable to confer avirulence."
Identification and fine mapping of Pi33, the rice resistance gene corresponding to the Magnaporthe grisea avirulence gene ACE1.
Expression of Magnaporthe grisea avirulence gene ACE1 is connected to the initiation of appressorium-mediated penetration.
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ACE1 is expressed only in appressoria at the onset of penetration, independently of host signals.
"only expressed in appressoria during fungal penetration into rice and barley"
Magnaporthe grisea avirulence gene ACE1 belongs to an infection-specific gene cluster involved in secondary metabolism.
Heterologous expression of the avirulence gene ACE1 from the fungal rice pathogen Magnaporthe oryzae.
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ACE1 alone makes a heptaketide pyrone; with the trans-ER RAP1 it makes a tyrosine-containing nonaketide amide resembling the cytochalasan backbone.
"Coexpression of ACE1 with RAP1, which encodes a trans-acting ER, changed the biosynthetic pathway."
Investigating the Function of Cryptic Cytochalasan Cytochrome P450 Monooxygenases Using Combinatorial Biosynthesis.
UniProt entry G4MVZ2 (ACE1_PYRO7)
Deep research report on ACE1 (falcon)