GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000003
Gene Ontology annotation based on Enzyme Commission mapping
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10521492
The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1.
PMID:11278816
Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7.
PMID:14623119
Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP.
PMID:15236971
Structure of the C-terminal RING finger from a RING-IBR-RING/TRIAD motif reveals a novel zinc-binding domain distinct from a RING.
PMID:21145461
Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics.
PMID:21532592
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids.
PMID:21590270
The parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodies.
PMID:23059369
Human Homolog of Drosophila Ariadne (HHARI) is a marker of cellular proliferation associated with nuclear bodies.
PMID:23707686
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism.
PMID:24076655
TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes.
PMID:27565346
Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation.
PMID:28514442
Architecture of the human interactome defines protein communities and disease networks.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Reactome:R-HSA-1169394
ISGylation of IRF3
Reactome:R-HSA-1169395
ISGylation of viral protein NS1
Reactome:R-HSA-1169398
ISGylation of host protein filamin B
Reactome:R-HSA-1169402
ISGylation of E2 conjugating enzymes
Reactome:R-HSA-1169403
Interaction of E3 ligase with ISG15:E2 complex
Reactome:R-HSA-1169405
ISGylation of protein phosphatase 1 beta (PP2CB)
Reactome:R-HSA-1169406
ISGylation of host proteins
Reactome:R-HSA-1678843
ISGylation of protein translation regulator 4EHP
Reactome:R-HSA-9833482
PKR-mediated signaling
Reactome:R-HSA-9833973
ISGylation of PKR
Reactome:R-HSA-9837231
ISGylation of BECN1
Reactome:R-HSA-9927247
ISGylation of DDX58 (RIG-I)
file:human/ARIH1/ARIH1-deep-research-falcon.md
Falcon deep research synthesis for ARIH1
file:human/ARIH1/ARIH1-uniprot.txt
UniProt record for ARIH1