mut-14 (Q17978) review notes

Deep research: falcon timed out (exit 137) and perplexity-lite is unavailable. No
deep-research file was generated. The key primary paper PMID:24684932 is cached as
abstract only.

Key facts with provenance

• MUT-14 is a DEAD-box helicase redundant with SMUT-1 PMID:24684932.
• Its catalytic activity is required in vivo PMID:24684932.
• Endo-siRNAs are lost in the double mutant PMID:24684932.
• It is required for antisense-RNA-triggered silencing PMID:11809977.
• It is in Mutator foci, which are separate from P granules PMID:22713602.
• It is recruited by the MUT-16 B-C region PMID:30036386.

Decisions

• P granule (IBA, IEA): MODIFY to mutator focus. Nucleus IBA: over-annotated.
• Gamete generation and cell differentiation IBA (Vasa/GLH node): over-annotated.
• NEW siRNA processing (IGI, PMID:24684932). Comparator check: MUT-16, RDE-2, RDE-8 and
  NYN-1/2 carry GO:0030422.