GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000003
Gene Ontology annotation based on Enzyme Commission mapping
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
GO_REF:0000116
Automatic Gene Ontology annotation based on Rhea mapping
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:12154078
Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in Neuro-2A cells.
PMID:1437147
PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family.
PMID:16091426
PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport.
PMID:19524571
Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1.
PMID:22184064
Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis.
PMID:22796189
Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase.
PMID:22798068
Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:25852190
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
PMID:26496610
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
PMID:28514442
Architecture of the human interactome defines protein communities and disease networks.
PMID:32098961
AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy.
PMID:32707033
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:35271311
OpenCell: Endogenous tagging for the cartography of human cellular organization.
PMID:36931259
A central chaperone-like role for 14-3-3 proteins in human cells.
file:human/CDK16/CDK16-uniprot.txt
UniProt record Q00536 (CDK16_HUMAN)
PMID:10511311
PCTAIRE-1: characterization, subcellular distribution, and cell cycle-dependent kinase activity.
PMID:12084709
Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35.
PMID:16461345
Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis.
PMID:21335063
Cyclin-dependent kinase 5-dependent phosphorylation of Pctaire1 regulates dendrite development.
PMID:25205104
PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells.
PMID:26205494
Cyclin Y phosphorylation- and 14-3-3-binding-dependent activation of PCTAIRE-1/CDK16.
PMID:26305884
CCNYL1, but Not CCNY, Cooperates with CDK16 to Regulate Spermatogenesis in Mouse.
PMID:28057719
Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16.
PMID:30880224
Identification of novel PCTAIRE-1/CDK16 substrates using a chemical genetic screen.
PMID:30992425
Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex.
PMID:41857027
Structural basis of the cyclin Y/14-3-3 protein-mediated activation of CDK16.
PMID:42774886
PP2A and CDK16 antagonistically regulate WIPI2B phosphorylation and neuronal autophagosome biogenesis.
PMID:9197417
The Cdk-like protein PCTAIRE-1 from mouse brain associates with p11 and 14-3-3 proteins.
PMID:25644381
X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes.
PMID:20534669
Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development.