Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Combined Automated Annotation using Multiple IEA Methods
Cloning and characterization of hGMEB1, a novel glucocorticoid modulatory element binding protein.
Small heat shock protein 27 (HSP27) associates with tubulin/microtubules in HeLa cells.
Chaperone hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes.
Inhibition of Daxx-mediated apoptosis by heat shock protein 27.
Alteration of protein-protein interactions of congenital cataract crystallin mutants.
Interaction of human HSP22 (HSPB8) with other small heat shock proteins.
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.
Self-association of a small heat shock protein.
Copurification of small heat shock protein with alpha B crystallin from human skeletal muscle.
Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis.
A human protein-protein interaction network: a resource for annotating the proteome.
Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.
Identification of differential proteins in nasopharyngeal carcinoma cells with p53 silence by proteome analysis.
HSP27 and HSP70 interact with CD10 in C4-2 prostate cancer cells.
The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter.
Construction and characterization of a normalized yeast two-hybrid library derived from a human protein-coding clone collection.
Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
HSPB7 is a SC35 speckle resident small heat shock protein.
Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy.
Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.
Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis.
ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair.
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.
Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation.
Dynamic protein-protein interaction wiring of the human spliceosome.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
Binding determinants of the small heat shock protein, αB-crystallin: recognition of the 'IxI' motif.
Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.
Charcot-Marie-Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments.
Structure and properties of G84R and L99M mutants of human small heat shock protein HspB1 correlating with motor neuropathy.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.
The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.
Small Heat Shock Protein Beta-1 (HSPB1) Is Upregulated and Regulates Autophagy and Apoptosis of Renal Tubular Cells in Acute Kidney Injury.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Axonal Neuropathies due to Mutations in Small Heat Shock Proteins: Clinical, Genetic, and Functional Insights into Novel Mutations.
Architecture of the human interactome defines protein communities and disease networks.
Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of 'quasi-ordered' states.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis.
Multimodal cell maps as a foundation for structural and functional genomics.
A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress.
AUF1 binds translation and heat shock proteins
AUF1 (hnRNP D0) is ubiquitinylated
p-MAPK2/3 phosphorylates HSP27
p-S MAPKAPK5 phosphorylates HSPB1
HSBP1 oligomer binds ESRs
ZDHHC7, ZDHHC21 palmitoylate ESR1
UniProtKB entry P04792 (HSPB1_HUMAN)