PA5498 (ZnuA, Q9HT75) review notes

No deep-research provider was available. Sources: UniProt Q9HT75 (unreviewed), cached PMID:26290475
(full text), PMID:24086521 (full text), PMID:9680209 (abstract).

Function

High-affinity zinc solute-binding protein of ZnuABC PMID:26290475.
Delta-znuA: PMID:26290475.
Binding: PMID:26290475.
Growth under zinc depletion: PMID:24086521.

PseudoCAP IBA-seed assessment

PTN node	node term	n_seeds	leaf IBAs	seed annotation (term, evidence, PMID)	verdict	rationale	other seeds	IBD stands without this seed?
PTN000767207	GO:0006829 zinc ion transport	2	24 (20 taxa)	GO:0006829, IMP, PMID:26290475 (PseudoCAP)	SOUND	Full text: ICP-MS shows a 60% zinc loss in Delta-znuA with other metals unchanged, and purified ZnuA binds zinc at nM affinity; the binding protein is a working part of the importer. Node term suits a ZnuA clade.	E. coli ZnuA (P39172; Patzer & Hantke 1998)	Yes. No defect.

The rows on this gene for zinc ion transport are marked TOO_GENERAL only because zinc ion
transmembrane transport (GO:0071577) is accepted; the claim itself is sound.

Non-seed PseudoCAP rows with defects: ISS GO:0000006 (enables a transmembrane transporter activity;
should be contributes_to GO:0015633, WRONG_QUALIFIER, PROBABLE) and IMP GO:0010043 response to zinc ion
(indirect growth phenotype; DELETE_ROW, PROBABLE).

Consistency with np20 (Zur)

np20 (PA5499) represses znuA; its review's nodes (PTN002112386, PTN002112441) are not shared with
PA5498. No node-level coordination needed.