UniProtKB:O08775
UniProt entry for rat Kdr (Vascular endothelial growth factor receptor 2, VGFR2_RAT)
file:rat/Kdr/Kdr-deep-research-manual.md
Manual literature synthesis for rat Kdr (VEGFR-2, O08775)
GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
GO_REF:0000121
RGD ISO annotations to rat from other mammalian species
PMID:11934468
Angiogenic and astroglial responses to vascular endothelial growth factor administration in adult rat brain.
PMID:12052848
KDR (VEGF receptor 2) is the major mediator for the hypotensive effect of VEGF.
PMID:14612527
Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy.
PMID:15258583
VEGF links hippocampal activity with neurogenesis, learning and memory.
PMID:15780476
Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed to hypoxia.
PMID:15785231
VEGF and VEGF receptor expression after experimental brain contusion in rat.
PMID:15885787
Differential expression of vascular endothelial growth factor implies the limbal origin of pterygia.
PMID:15951738
Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor.
PMID:16329123
Vascular endothelial growth factor stimulates neurite outgrowth from cerebral cortical neurons via Rho kinase signaling.
PMID:16672722
Vascular endothelial growth factor and kinase domain region receptor are involved in both seminiferous cord formation and vascular development during testis morphogenesis in the rat.
PMID:17360578
VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants.
PMID:17881084
Heparin affin regulatory peptide/pleiotrophin negatively affects diverse biological activities in C6 glioma cells.
PMID:18221855
Vascular endothelial growth factor (VEGF) signaling regulates hippocampal neurons by elevation of intracellular calcium and activation of calcium/calmodulin protein kinase II and mammalian target of rapamycin.
PMID:18614764
Astrocyte responses to injury: VEGF simultaneously modulates cell death and proliferation.
PMID:20187850
Multiple receptor tyrosine kinases are expressed in adult rat retinal ganglion cells as revealed by single-cell degenerate primer polymerase chain reaction.
PMID:25942475
TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis.
PMID:9160888
The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-gamma pathway and partially induces mitotic signals in NIH3T3 fibroblasts.
PMID:9442048
Two functional forms of vascular endothelial growth factor receptor-2/Flk-1 mRNA are expressed in normal rat retina.
PMID:20097747
Hyaluronan mixed esters of butyric and retinoic acid affording myocardial survival and repair without stem cell transplantation.