Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Electronic Gene Ontology annotations created by ARBA machine learning models
Unusual structural organization of the endocytic proteins AP180 and epsin 1.
Clint: a novel clathrin-binding ENTH-domain protein at the Golgi.
Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.
Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference.
Clathrin is required for the function of the mitotic spindle.
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Clathrin localizes to mitotic spindle
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Clathrin depletion causes mitotic defects
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Clathrin required for receptor-mediated endocytosis
SNX9 as an adaptor for linking synaptojanin-1 to the Cdc42 effector ACK1.
A human protein-protein interaction network: a resource for annotating the proteome.
Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation.
Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases.
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Human clathrin heavy chain (CLTC): partial molecular cloning, expression, and mapping of the gene to human chromosome 17q11-qter.
A B-Myb complex containing clathrin and filamin is required for mitotic spindle function.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism.
A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism.
Quantitative proteomics identifies a Dab2/integrin module regulating cell migration.
Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor.
Defining the membrane proteome of NK cells.
The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation.
A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging.
Protein profile of exosomes from trabecular meshwork cells.
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
KIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerization.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Murine homologue of the human KIAA1199 is implicated in hyaluronan binding and depolymerization.
Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.
A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells.
CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.
Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level.
LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson's disease.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs.
Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.
Multimodal cell maps as a foundation for structural and functional genomics.
Clathrin structure characterized with monoclonal antibodies. II. Identification of in vivo forms of clathrin.
Axonal transport of NGF:Trk complexes
Uncoating of clathrin-coated vesicles and fusion with endosomes
TGN-lysosomal vesicle coat assembly
Recruitment of clathrin coated vesicle by Ii
Translocation of TGN-lysosome vesicle to lysosome
Internalization of MHC II:Ii clathrin coated vesicle
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome
L1 binds to AP-2 Clathrin complex
Transport of L1 into endosomes
trans-Golgi Network Coat Assembly
trans-Golgi Network Vesicle Scission
trans-Golgi Network Derived Vesicle Uncoating
trans-Golgi Network Derived Lysosomal Vesicle Uncoating
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly
trans-Golgi Network Lysosomal Vesicle Scission
Reinsertion of L1 into the plasma membrane
Phosphorylation of L1 by ERK
p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis
WNT5A:FZD4 is endocytosed
CLAT:AP1:CLVS bind PI(3,5)P2
Formation of clathrin coated vesicle
PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome
PCSK9:LDLR bind to Clathrin
Degradation of PCSK9:LDLR:Clathrin-coated vesicle
VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane
VLDLR:PCSK9 binds Clathrin-coated vesicles
Recruitment of AP-2 complex and clathrin
AAK1 phosphorylates AP-2 mu subunit at T156
FCHo proteins bind nascent clathrin-coated pit
Epsin family proteins bind ubiquitinated cargo
ARRB recruits GPCRs into clathrin-coated pits
F- and N- BAR domain proteins bind the clathrin-coated pit
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit
Clathrin recruits PIK3C2A
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
SNX9 recruits components of the actin polymerizing machinery
BAR domain proteins recruit dynamin
SYNJ hydrolyze PI(4,5)P2 to PI(4)P
Endophilins recruit synaptojanins to the clathrin-coated pit
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating
Clathrin recruits auxilins to the clathrin-coated vesicle
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle
Dynamin-mediated GTP hydrolysis promotes vesicle scission
Dissociation of clathrin-associated proteins
Dissociation of AAK1 and dephosphorylation of AP-2 mu2
RAB5 and GAPVD1 bind AP-2
Initial binding of AP-2 and clathrin to PI(4,5)P2
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex
ALK mutants bind type I TKIs
Ligand-independent dimerization of ALK fusions
Autophosphorylation of ALK fusions
PI3K synthesizes PIP3 downstream of ALK mutants
ALK mutants phosphorylate STAT3
pY-STAT3 dimer translocates to the nucleus downstream of ALK mutants
Deep research report on CLTC