Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Small regulatory RNAs inhibit RNA polymerase II during the elongation phase of transcription.

A pre-mRNA-associating factor links endogenous siRNAs to chromatin regulation.

Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint.

A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality.

NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.

Antisense ribosomal siRNAs inhibit RNA polymerase I-directed transcription in C. elegans.

The nuclear Argonaute HRDE-1 directs target gene re-localization and shuttles to nuage to promote small RNA-mediated inherited silencing.