Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Dynamin II is involved in endocytosis but not in the formation of transport vesicles from the trans-Golgi network.
Evidence that dynamin-2 functions as a signal-transducing GTPase.
Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton.
Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference.
Dynamin 2 binds gamma-tubulin and participates in centrosome cohesion.
SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.
Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth disease.
Mutations in dynamin 2 cause dominant centronuclear myopathy.
TTP specifically regulates the internalization of the transferrin receptor.
Complexes of syndapin II with dynamin II promote vesicle formation at the trans-Golgi network.
Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.
Two mechanistically distinct forms of endocytosis in adrenal chromaffin cells: Differential effects of SH3 domains and amphiphysin antagonism.
Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis.
Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef.
Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy.
A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein.
SNX9 regulates tubular invagination of the plasma membrane through interaction with actin cytoskeleton and dynamin 2.
The PCH family member proline-serine-threonine phosphatase-interacting protein 1 targets to the leukocyte uropod and regulates directed cell migration.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Charting the molecular network of the drug target Bcr-Abl.
Dynamin2 GTPase and cortactin remodel actin filaments.
Dynamin 2 mutations associated with human diseases impair clathrin-mediated receptor endocytosis.
A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding.
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.
PEX14 is required for microtubule-based peroxisome motility in human cells.
Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.
A directed protein interaction network for investigating intracellular signal transduction.
Toward an understanding of the protein interaction network of the human liver.
Identification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2.
Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
The myopathy-causing mutation DNM2-S619L leads to defective tubulation in vitro and in developing zebrafish.
Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling.
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin-2.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS(G13D).
A reference map of the human binary protein interactome.
A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy.
Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Gain-of-Function Properties of a Dynamin 2 Mutant Implicated in Charcot-Marie-Tooth Disease.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
GSK3α phosphorylates dynamin-2 to promote GLUT4 endocytosis in muscle cells.
Multimodal cell maps as a foundation for structural and functional genomics.
Isolation of an ubiquitously expressed cDNA encoding human dynamin II, a member of the large GTP-binding protein family.
trans-Golgi Network Vesicle Budding
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP
NOSTRIN mediated translocation of eNOS from plasma membrane
eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2
TGN-lysosomal vesicle coat assembly
Translocation of TGN-lysosome vesicle to lysosome
MHC class II antigen presentation
trans-Golgi Network Coat Assembly
trans-Golgi Network Vesicle Scission
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly
trans-Golgi Network Lysosomal Vesicle Scission
BAR domain proteins recruit dynamin
SYNJ hydrolyze PI(4,5)P2 to PI(4)P
Endophilins recruit synaptojanins to the clathrin-coated pit
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating
Clathrin recruits auxilins to the clathrin-coated vesicle
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle
Dynamin-mediated GTP hydrolysis promotes vesicle scission
Dissociation of clathrin-associated proteins
Dissociation of AAK1 and dephosphorylation of AP-2 mu2
RAB5 and GAPVD1 bind AP-2
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex
Lava lamp, a novel peripheral golgi protein, is required for Drosophila melanogaster cellularization.
Synaptic vesicles: test for a role in presynaptic calcium regulation.
A pathway for phagosome maturation during engulfment of apoptotic cells.
Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells.
Phosphorylation of dynamin II at serine-764 is associated with cytokinesis.
Growth cone morphology and spreading are regulated by a dynamin-cortactin complex at point contacts in hippocampal neurons.
The Lipid-Binding Defective Dynamin 2 Mutant in Charcot-Marie-Tooth Disease Impairs Proper Actin Bundling and Actin Organization in Glomerular Podocytes.