Combined Automated Annotation using Multiple IEA Methods
UniProtKB entry A0A0H2LZ72 (A0A0H2LZ72_VARPD): Urease accessory protein UreF
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VPARA_50930 (A0A0H2LZ72, ureF) is a 223-residue cytoplasmic urease accessory protein (HAMAP rule MF_01385, InterPro IPR002639, PANTHER PTHR33620:SF1) that forms part of the UreD-UreF-UreG chaperone complex required for maturation of the urease nickel metallocenter.
"CC -!- FUNCTION: Required for maturation of urease via the functional
CC incorporation of the urease nickel metallocenter. {ECO:0000256|HAMAP-
CC Rule:MF_01385}."
Klebsiella aerogenes UreF: identification of the UreG binding site and role in enhancing the fidelity of urease activation.
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UreF provides the binding surface that recruits UreG to the UreD-apourease complex and gates UreG GTPase activity to enhance the fidelity of nickel metallocenter assembly against noncognate metals.
"Further experiments with these complexes provided evidence that UreF gates the GTPase activity of UreG to enhance the fidelity of urease metallocenter assembly, especially in the presence of the noncognate metal Zn."
Complete genome sequence of the metabolically versatile plant growth-promoting endophyte Variovorax paradoxus S110.
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Genomic analysis of Variovorax paradoxus highlights its diverse metabolic capabilities in soil and plant-associated environments.
"Variovorax paradoxus is a microorganism of special interest due to its diverse metabolic capabilities, including the biodegradation of both biogenic compounds and anthropogenic contaminants."