SCAP (CG33131; UniProt A1Z6J2) notes

• ER membrane escort of SREBP (UniProt function by similarity; WD40 + sterol-sensing domain).
• In flies SREBP processing is controlled by phosphatidylethanolamine, not sterols
  PMID:11988566.
• Insects are sterol auxotrophs PMID:9632664
  -> IBA "positive regulation of cholesterol biosynthetic process" REMOVED (taxon mismatch; propagation_review added); IEA sterol binding marked over-annotated.
• Core MF chosen: protein carrier activity (GO:0140597; "Directly binding to a protein and delivering it either to an acceptor molecule or to a specific location") for the SREBP escort role; no existing GOA MF row.
• Deep research: falcon run killed in the first attempt (exit 137, memory pressure on the shared host); a retry was stopped unfinished after the other genes completed. No deep-research file exists, so notes are based on cached publications.