Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Expression of the Mf1 gene in developing mouse hearts: implication in the development of human congenital heart defects.

Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1.

DSCAM, a highly conserved gene in mammals, expressed in differentiating mouse brain.

The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis.

FOXC1 transcriptional regulation is mediated by N- and C-terminal activation domains and contains a phosphorylated transcriptional inhibitory domain.

Identification of FOXC1 as a TGF-beta1 responsive gene and its involvement in negative regulation of cell growth.

A family with Axenfeld-Rieger syndrome and Peters Anomaly caused by a point mutation (Phe112Ser) in the FOXC1 gene.

Structural and functional analyses of disease-causing missense mutations in the forkhead domain of FOXC1.

Identification and analysis of a novel mutation in the FOXC1 forkhead domain.

The wing 2 region of the FOXC1 forkhead domain is necessary for normal DNA-binding and transactivation functions.

Essential structural and functional determinants within the forkhead domain of FOXC1.

FOXC1 transcriptional regulatory activity is impaired by PBX1 in a filamin A-mediated manner.

Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld-Rieger syndrome and anterior segment dysgenesis.

Regulation of FOXC1 stability and transcriptional activity by an epidermal growth factor-activated mitogen-activated protein kinase signaling cascade.

Analyses of a novel L130F missense mutation in FOXC1.

FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A.

Human p32 is a novel FOXC1-interacting protein that regulates FOXC1 transcriptional activity in ocular cells.

Severe molecular defects of a novel FOXC1 W152G mutation result in aniridia.

Characterization of a novel FOXC1 mutation, P297S, identified in two individuals with anterior segment dysgenesis.

FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer.

Global landscape of HIV-human protein complexes.

FOXC1 contributes to microvascular invasion in primary hepatocellular carcinoma via regulating epithelial-mesenchymal transition.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

Hypo- and hypermorphic FOXC1 mutations in dominant glaucoma: transactivation and phenotypic variability.

FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer.

Comparison of Bioinformatics Prediction, Molecular Modeling, and Functional Analyses of FOXC1 Mutations in Patients with Axenfeld-Rieger Syndrome.

Forkhead Box C1 Regulates Human Primary Keratinocyte Terminal Differentiation.

Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

Drosophila forkhead homologues are expressed in a lineage-restricted manner in human hematopoietic cells.

Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly.

Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract.

Foxc1 and Foxc2 are necessary to maintain glomerular podocytes.

Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation.

Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth.

The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification.

Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration.

FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation.