GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000116
Automatic Gene Ontology annotation based on Rhea mapping
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10511556
Genetic analysis of rolled, which encodes a Drosophila mitogen-activated protein kinase.
PMID:10652276
Relief of gene repression by torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning.
PMID:10823906
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.
PMID:11850406
KSR is a scaffold required for activation of the ERK/MAPK module.
PMID:11919715
The Hopscotch Jak kinase requires the Raf pathway to promote blood cell activation and differentiation in Drosophila.
PMID:15337530
Drosophila PI3 kinase and Akt involved in insulin-stimulated proliferation and ERK pathway activation in Schneider cells.
PMID:15634694
FGF signalling and the mechanism of mesoderm spreading in Drosophila embryos.
PMID:16600911
The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor signaling pathway.
PMID:16600912
A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila.
PMID:17011495
An intrinsic cell cycle checkpoint pathway mediated by MEK and ERK in Drosophila.
PMID:17637670
Two distinct modes of guidance signalling during collective migration of border cells.
PMID:18494562
Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila.
PMID:21297578
Drosophila Ras/MAPK signalling regulates innate immune responses in immune and intestinal stem cells.
PMID:21683597
Phosphorylation of Groucho mediates RTK feedback inhibition and prolonged pathway target gene expression.
PMID:22242005
MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila.
PMID:23980175
ERK signaling couples nutrient status to antiviral defense in the insect gut.
PMID:24643257
A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila.
PMID:25061859
Slik and the receptor tyrosine kinase Breathless mediate localized activation of Moesin in terminal tracheal cells.
PMID:25130174
Switching between humoral and cellular immune responses in Drosophila is guided by the cytokine GBP.
PMID:25749252
A systems-level interrogation identifies regulators of Drosophila blood cell number and survival.
PMID:26119340
The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity.
PMID:28166211
Divergent effects of intrinsically active MEK variants on developmental Ras signaling.
PMID:29433126
MEK drives BRAF activation through allosteric control of KSR proteins.
PMID:7958887
A temperature-sensitive MEK mutation demonstrates the conservation of the signaling pathways activated by receptor tyrosine kinases.
PMID:8033205
The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway.
PMID:8381718
A protein kinase similar to MAP kinase activator acts downstream of the raf kinase in Drosophila.
PMID:8722784
A screen for genes that function downstream of Ras1 during Drosophila eye development.
PMID:8798773
Biochemical characterization of rolledSem, an activated form of Drosophila mitogen-activated protein kinase.
PMID:9136016
Dominant mutations of Drosophila MAP kinase kinase and their activities in Drosophila and yeast MAP kinase cascades.
Reactome:R-DME-209196
Phosphorylation of CI by PKA-C1
Reactome:R-DME-209341
Phosphorylation of SMO by PKA-C1
Reactome:R-DME-432535
TIM is phosphorylated by CK2
Reactome:R-DME-432590
Phosphorylated PER is phosphorylated by CK2