Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency.
The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway.
Apolipoprotein specificity for lipid efflux by the human ABCAI transporter.
Characterization of the ATPase cycle of human ABCA1: implications for its function as a regulator rather than an active transporter.
The ATP binding cassette transporter A1 contributes to the secretion of interleukin 1beta from macrophages but not from monocytes.
Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I.
Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter.
The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease.
Molecular interactions between apoE and ABCA1: impact on apoE lipidation.
Impaired platelet activation in familial high density lipoprotein deficiency (Tangier disease).
Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism.
Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells.
Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.
Apolipoprotein A-I activates Cdc42 signaling through the ABCA1 transporter.
Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1.
The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins.
Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus.
Palmitoylation of ATP-binding cassette transporter A1 is essential for its trafficking and function.
ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis.
Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants.
MicroRNA-19b promotes macrophage cholesterol accumulation and aortic atherosclerosis by targeting ATP-binding cassette transporter A1.
HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin.
Lysophosphatidylcholine export by human ABCA7.
Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis.
Apolipoprotein A-I directly interacts with extracellular domain 1 of human ABCA1.
ABCA1 is an extracellular phospholipid translocase.
Quantitative fragmentomics allow affinity mapping of interactomes.
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane
4xPALM-C-p-2S-ABCA1 tetramer binds APOA1
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane
ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane
Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane
UniProt text export for ABCA1 (O95477)
Manual ABCA1 review notes