GO_REF:0000033

Annotation inferences using phylogenetic trees

PAINT infers inherited regulatory activities from manually placed ancestral-node assertions.

GO_REF:0000052

Gene Ontology annotation based on curation of immunofluorescence data

Curated human immunofluorescence supports nucleoplasmic and context-dependent cytoplasmic DPF2 pools.

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

Combined electronic inference summarizes nuclear and cytoplasmic localization.

PMID:10078207

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.

Purified human SWI/SNF core subunits support ATP-dependent nucleosome remodeling.

PMID:10778858

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.

Rb-associated SWI/SNF repressor complexes regulate cell-cycle progression.

PMID:11790558

SWI/SNF chromatin remodeling and cancer.

SWI/SNF complexes connect transcriptional regulation with cancer-associated cell-cycle control.

PMID:12192000

REST repression of neuronal genes requires components of the hSWI.SNF complex.

REST/CoREST repression involves SWI/SNF-associated chromatin regulation.

PMID:12215535

The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.

SWI/SNF promotes excision-nuclease repair in a damaged mononucleosome context.

PMID:16217013

Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region.

Human K562 LARC preparations contain requiem/DPF2 identified by mass spectrometry.

PMID:18809673

BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.

Tagged BAF45D associates with SWI/SNF complexes containing BRG1 and ARID subunits.

PMID:19279220

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.

Mouse esBAF complexes support embryonic-stem-cell self-renewal and pluripotency.

PMID:25066234

Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin.

PBAF supports transcriptional silencing near DNA breaks and efficient repair in the tested cells.

PMID:25416956

A proteome-scale map of the human interactome network.

The binary interactome contains DPF2 interactions with LDOC1 and LNX1.

PMID:28533407

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.

DPF2 histone recognition supports chromatin recruitment and inhibition of myeloid differentiation.

PMID:29429572

Mutations in the BAF-Complex Subunit DPF2 Are Associated with Coffin-Siris Syndrome.

Coffin-Siris-associated PHD variants impair histone interaction and alter DPF2 nuclear distribution.

PMID:32296183

A reference map of the human binary protein interactome.

HuRI identifies a set of sequence-authenticated DPF2 binary interaction partners.

PMID:7961935

Requiem: a novel zinc finger gene essential for apoptosis in myeloid cells.

Mouse Requiem antisense suppression permits survival of FDCP-1 cells after IL-3 withdrawal.

PMID:8804307

Diversity and specialization of mammalian SWI/SNF complexes.

Mammalian SWI/SNF complexes contain conserved and specialized accessory subunits.

PMID:8812431

The d4 gene family in the human genome.

The human d4-family study identifies and maps the human Requiem-related gene.

Reactome:R-HSA-9825847

MITF-M dimer and the SWI/SNF complex bind the TYRP1 promoter

Models MITF-M and SWI/SNF recruitment to the TYRP1 promoter with an explicit DPF2-containing candidate path.

Reactome:R-HSA-9932836

DPF1,2,3 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1

Models binding of a DPF1/2/3 candidate set to the remodeling scaffold.

Reactome:R-HSA-9933238

SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3

Models addition of an SS18-containing ATPase module to a DPF-containing scaffold.

Reactome:R-HSA-9934021

Formation of neuronal progenitor BAF (npBAF)

Models formation of npBAF with a DPF2-containing candidate path.

Reactome:R-HSA-9934022

DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A

Models binding of DPF2/PHF10 alternatives to a scaffold assembly.

Reactome:R-HSA-9934024

SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10

Models addition of a SMARCA4/BCL11-containing ATPase module to a DPF2-containing scaffold.

PMID:20460684

Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway.

DPF2 links RelB/p52 with Brm-type SWI/SNF and supports noncanonical NF-kappaB-dependent transcription.

PMID:27775714

Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2.

Human DPF2 tandem PHD fingers recognize H3K14 crotonylation with high affinity.